VITAMIN C

Vitamin C Derivatives

Also known as: SAP, MAP, Ethyl Ascorbic Acid, Tetrahexyldecyl Ascorbate

pH pH 5-7 (skin-friendly)SAP: 2-5%, MAP: 10-15%, Ethyl Ascorbic: 3-15%, THD: 1-5%

What is Vitamin C Derivatives?

Stable forms of Vitamin C that are gentler and more pH-friendly than L-Ascorbic Acid. They convert to ascorbic acid in the skin. Less potent but better tolerated and no pH conflicts.

Key Benefits

  • Brightening effects (slower than L-AA)
  • Antioxidant protection
  • Gentle on sensitive skin
  • No pH conflicts with other actives
  • Longer shelf life
  • Less irritation

🎯Best For

Sensitive skinBeginnersCombining with niacinamide or retinoidsOily/acne-prone (SAP)

📋How to Use

Can be used AM or PM. No special pH requirements. Layer easily with other actives. Wait time not necessary. More stable - less urgency to replace.

⚗️RECOMMENDED CONCENTRATION: SAP: 2-5%, MAP: 10-15%, Ethyl Ascorbic: 3-15%, THD: 1-5%

⚠️Avoid Mixing With

  • Generally none - very compatible

💚Pairs Well With

  • Niacinamide
  • Retinoids
  • Peptides
  • AHAs/BHAs
  • Hyaluronic Acid

🚫Avoid If

  • Rarely problematic - safe for most

🔬Scientific Evidence

SAP shown to reduce acne by 48% in 12 weeks. MAP penetrates well but converts slower. Ethyl Ascorbic Acid and THD have excellent stability profiles. Studies show 30-50% efficacy compared to L-AA.

Important Warnings

  • !Slower results than L-Ascorbic Acid
  • !May need higher concentrations for visible effects
  • !THD is oil-soluble (different texture)

💡Fun Facts

  • SAP (Sodium Ascorbyl Phosphate) also treats acne
  • THD is the most stable and pH-flexible
  • Great for layering with niacinamide (no flushing)
  • MAP is water-soluble, THD is oil-soluble

Want to Check Your Routine?

Analyze your full skincare routine for conflicts with Vitamin C Derivatives and other actives